Annual influenza vaccination is recommended for all persons ≥6 months old without a contraindication.1-6 Influenza vaccines available this season in the US are listed in Table 3.
COMPOSITION — All influenza vaccines available in the US this season are trivalent: they contain two influenza A virus antigens and one influenza B virus antigen (see Table 1). Influenza A viruses are the primary cause of influenza-related morbidity and mortality, especially in older adults. Illness caused by...
RELEASE
The FDA has approved the nonsteroidal mineralocorticoid receptor antagonist (MRA) finerenone (Kerendia) to reduce the urinary albumin-to-creatinine ratio (UACR) in adults with chronic kidney disease (CKD) associated with type 1 diabetes. Reducing UACR is expected to reduce the risk of sustained eGFR decline and progression to end-stage kidney disease. Finerenone is the first drug to be approved in the US for this indication in 30 years.
OTHER INDICATIONS — Finerenone is also FDA-approved to reduce the risk of kidney disease progression and cardiovascular events in adults with CKD associated with type 2 diabetes and to reduce the risk of cardiovascular death, hospitalization for heart failure (HF), and urgent HF visits in adults with HF with a left ventricular ejection fraction (LVEF) ≥40%.1,2
MECHANISM OF ACTION — CKD and cardiovascular disease are common complications of type 1 …